反应详情

The title compound was prepared following the procedure described for Step-5 of Intermediate-55 using methyl 7-[(2-chloro-6-fluorophenyl)amino]-2-methyl-8H-imidazo[4,5-e][1,3]benzoxazole-4-carboxylate (0.190 g, 0.508 mmol), MeOH (3.0 mL) and sodium hydroxide (0.101 g, 2.52 mmol) to afford 0.136 g of the desired product. 1HNMR (DMSO-d6): δ 2.60 (s, 3H), 7.35 (s, 2H), 7.44 (s, 1H), 7.64 (s, 1H), 12.0-13.0 (s, 3H); MS [M+H]+: 360.2.

1. customThe title compound was prepared