反应详情

The title compound was prepared in a manner similar to that described in Example 27, Step H from methyl 2-(tert-butoxy)-2-(4-(chroman-6-yl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)acetate and 2,3-difluorobenzyl bromide. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 7.49-7.43 (m, 1 H), 7.20-7.04 (m, 5 H), 6.94 (dd, J=4.9, 8.4 Hz, 1 H), 6.32 (dd, J=3.5, 11.1 Hz, 1 H), 5.75-5.53 (m, 3 H), 4.33-4.26 (m, 2 H), 3.00-2.81 (m, 2 H), 2.79 (s, 3 H), 2.17-2.07 (m, 2 H), 0.97 (s, 9 H); LC/MS (m/z) ES+=521.33 (M+1).