反应详情

The titled compound (yield=7%) was prepared using a procedure analogous to that described in connection with 10 (Example 10) except 3-(trifluoromethyl)-1H-pyrazol-4-ylboronic acid and 1D (Example 1) were used as starting materials. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.47 (s, 6H) 7.67 (d, J=8.34 Hz, 2H) 7.76 (d, J=8.34 Hz, 1H) 8.11 (d, J=8.34 Hz, 2H) 8.20 (d, J=8.59 Hz, 1H) 8.57 (s, 1H) 12.97 (s, 1H) 13.88 (br. s., 1H); ESI-MS: m/z 448.0 (M+H)+.