反应详情

The titled compound (yield=15%, white solid) was prepared using a procedure analogous to that described in connection with 9 (Example 9) except 4-(methylcarbamoyl)phenylboronic acid and 2F (Example 2) were used as starting materials. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.27 (s, 6H) 2.82 (d, J=4.55 Hz, 3H) 3.49 (d, J=5.31 Hz, 2H) 4.75-4.81 (m, 1H) 7.58 (d, J=8.84 Hz, 2H) 7.98 (d, J=8.59 Hz, 2H) 8.11 (d, J=8.84 Hz, 2H) 8.17-8.22 (m, 1H) 8.22-8.28 (m, 3H) 8.56 (q, J=4.63 Hz, 1H) 13.02 (s, 1H); ESI-MS: m/z 461.0 (M+H)+.