反应详情

13.8 9 (29.7 mmol) of 5-[di-(tert-butoxycarbonyl)amino]methyl-7-nitro-2,3-dimethoxyquinoxaline are stirred at room temperature for 8 hours in 60 ml of trifluoroacetic acid. The reaction mixture is concentrated under reduced pressure and the red oil is well stirred at 0° for one hour with 1N potassium carbonate. The yellow crystals are filtered off, washed with 100 ml of water and 100 ml of a 1:1 mixture of ethyl acetate and hexane, and dried.

1. concentrationThe reaction mixture is concentrated under reduced pressure
2. filtrationThe yellow crystals are filtered off
3. washwashed with 100 ml of water and 100 ml of a 1:1 mixture of ethyl acetate and hexane
4. customdried