4-Aminothiophenol → HCID 178434132, compound

HRID 1987598Notes

Reaction equation

HRID 1987598 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5]/[C:4](=[C:12]2/[C:13]([CH3:18])=[N:14][NH:15][C:16]/2=[O:17])/[CH:3]=1.[NH2:19][C:20]1[CH:25]=[CH:24][C:23]([SH:26])=[CH:22][CH:21]=1>>[NH2:19][C:20]1[CH:25]=[CH:24][C:23]([S:26][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[NH:5]/[C:4](=[C:12]3/[C:13]([CH3:18])=[N:14][NH:15][C:16]/3=[O:17])/[CH:3]=2)=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 145104-AminothiophenolHCID 178434119HCID 178434119, compound

Product 1

HCID 178434132HCID 178434132, compound

Procedure

The title compound was prepared from (Z)-4-(4-chloroquinolin-2(1H)-ylidene)-3-methyl-1H-pyrazol-5(4H)-one and 4-aminothiophenol using the procedure described in Example 6. 1H NMR (400 MHz, CHLOROFORM-D) δ ppm 1.97 (s, 3H) 6.77-6.79 (m, 3H) 7.33 (d, J=8.34 Hz, 2H) 7.64 (t, J=7.45 Hz, 1H) 7.88 (t, J=7.83 Hz, 1H) 7.96 (d, J=8.59 Hz, 1H) 8.14 (d, J=8.08 Hz, 1H); ESI-MS: m/z calc'd for C19H16N4OS 348.10. found 349.2 (M+H)+.

Sources & evidence

ORD record
ord-70ceb7bd502e4c7fbb690f0103b12d00
Source dataset
uspto-grants-2009_06
Patent number
US07550598B2

Reaction notes

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