反应详情

The title compound was prepared from (Z)-4-(4-chloroquinolin-2(1H)-ylidene)-3-cyclopropyl-1H-pyrazol-5(4H)-one and N-(4-mercaptophenyl)cyclopropanecarboxamide under conditions similar to those described in Example 6. The final compound was purified by precipitating it from methanol. 1H NMR (400 MHz, DMSO-D6) δ ppm 0.17-0.29 (m, 2H) 0.47-0.59 (m, 2H) 0.77-0.87 (m, 4H) 1.05-1.17 (m, 1H) 1.74-1.84 (m, 1H) 6.96 (s, 1H) 7.49-7.60 (m, 1H) 7.68 (d, J=8.59 Hz, 2H) 7.77-7.81 (m, 4H) 8.06 (d, J=7.07 Hz, 1H) 10.52 (s, 1H) 11.03 (s, 1H) 11.82 (s, 1H); ESI-MS: m/z calc'd for C25H22N4O2S 442.15. found 443.3 (M+H)+.

1. customThe final compound was purified
2. customby precipitating it from methanol