HRID19886

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8083

Morpholine

C4H9NO

结构：CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1

HCID11603838

未命名化合物

结构：CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCOCC4)n(-c4ccnc(Cl)c4)c3cc2Br)CC1

HCID16739659

未命名化合物

结构：CC(C)N1CCC(Oc2cc3cc(C(=O)O)[nH]c3cc2Br)CC1.Cl

HCID67017930

未命名化合物

PRODUCTS

生成物

结构：CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCOCC4)[nH]c3cc2Br)CC1

HCID67017918

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for the synthesis of intermediate 1, step 4, the title compound was synthesized from 6-bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid hydrochloride salt with 1 eq. lithium chloride (example 41, step 5) and morpholine. The title compound was obtained in 75% yield as light yellow solid. MS (m/e): 450.1 (MH+, 100%).