反应详情

The procedure of Example 1 was employed utilizing N-benzylaniline and 4-phenoxyphenyl phosphonic dichloride. The reaction of the dilithio compound and the 4-phenoxyphenyl phosphonic dichloride was conducted at 0° C. The crude product produced as a result of the chromatographic separation was distilled at 140° C. and the resulting residue was crystallilzed from diethyl ether to yield 1-(4-phenoxyphenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide as beige needles. A second crop was obtained to give a total yield of 0.75 g, 3% yield of 1-(4-phenoxyphenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide having a melting point of 207°-208° C. and the following analysis:

1. customwas conducted at 0° C
2. customThe crude product produced as
3. customa result of the chromatographic separation
4. distillationwas distilled at 140° C.