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HRID2191229

反应详情

EQUATION

反应方程式

HRID 2191229 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCC[C@H]1COc1ccccc1
HCID10636271

(S)-tert-Butyl 2-(phenoxymethyl)pyrrolidine-1-carboxylate

C16H23NO3

结构：Cc1ccc(S(=O)(=O)OC[C@@H]2CCN2C(=O)OC(C)(C)C)cc1
HCID11602568

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CC[C@H]1COc1ccccc1
HCID11565179

未命名化合物

收率 79%

PROCEDURE

实验过程

(S)-tert-Butyl 2-(phenoxymethyl)azetidine-1-carboxylate (16) was prepared according to the same procedure for compound 9, except using compound 15, and purified with hexanes-ether (2:1) to afford 0.81 g (79%) of 16 as a colorless oil. 1H NMR (300 MHz, CDCl3) δ CDCl3 7.30 (m, 2H), 6.94 (m, 3H), 4.53 (m, 1H), 4.26 (m, 1H), 4.12 (m, 1H), 3.93 (m, 2H), 2.33 (m, 2H), 1.43 (s, 9H).

WORKUP

后处理

  1. custom(S)-tert-Butyl 2-(phenoxymethyl)azetidine-1-carboxylate (16) was prepared
  2. custompurified with hexanes-ether (2:1)