反应详情

The title compound was prepared in analogy to the procedure described for Step L3 but 5-bromo-2-[(4-chloro-phenyl)-hydroxy-methyl]-1-isopropyl-1H-pyrrole-3-carboxylic acid methyl ester (step D3) and 2,5-dimethyl-2H-pyrazol-3-ylamine [3524-32-1] were used instead of 2-[(4-chloro-phenyl)-hydroxy-methyl]-1-isopropyl-1H-pyrrole-3-carboxylic acid ethyl ester and 3-amino-5-chloro-1-methyl-1H-pyridin-2-one respectively. The title compound was obtained as a foam. ESI-MS: tR=1.29 min, [M+H]+ 479/481/483 (LC-MS 1); TLC: Rf=0.31 (1:1 CH2Cl2/EtOAc).

1. customThe title compound was prepared in analogy to the procedure