反应详情

Following the procedure described in the preceeding example but using 3-amino-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol and 2-thienylsulfonylchloride, the title compound was obtained in a similar yield: mp 169°-180° C.; 1H NMR (80 MHz, MeOH-d4)δ(TMS) 8.19 (s, 1H, CH=N), 7.74 (s, 1H, CH=N), 7.7-7.0 (m, 6H, arom), 4-95 (AB system, Δv=0.60, J=14.5 Hz, 2H, CH2 -Tr), 3.68 (AB system, Δv=0.13, J=14 Hz, 2H, CH2NH). Anal calcd. for C15H14Cl2N4O3S2 : C 41.58%; H 3.26%; N 12.93%. Found: C 42.39%; H 3.27%; N 13.06%.