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HRID2239736

反应详情

EQUATION

反应方程式

HRID 2239736 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(O)cc1
HCID9015

4-Methoxyphenol

C7H8O2

结构：CC(C)(C)N1C(=O)C(NCC(=O)O)=C(c2ccccc2)S1(=O)=O
HCID67241765

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(OC(=O)CNC2=C(c3ccccc3)S(=O)(=O)N(C(C)(C)C)C2=O)cc1
HCID67241876

未命名化合物

收率 21%

PROCEDURE

实验过程

The title compound was prepared from [(2-tert-butyl-1,1-dioxido-3-oxo-5-phenyl-2,3-dihydroisothiazol-4-yl)amino]acetic acid and 4-methoxyphenol as described for Example 171 affording the title compound (28 mg, 21%). 1H NMR (CDCl3, 400 MHz) δ 1.71 (s, 9H), 3.77 (s, 3H), 3.81 (d, 2H), 5.78 (t, 1H), 6.85 (dd, 4H), 7.44-7.51 (m, 5H). 13C NMR (CDCl3, 100 MHz) δ 27.8, 45.6, 55.8, 61.9, 110.1, 114.7, 122.0, 124.5, 129.1, 130.2, 131.6, 134.8, 143.6, 157.8, 159.2, 167.8.