反应详情

3-Bromo-6-methoxy-3H-isobenzofuran-1-one (41 g, 0.169 mole), prepared as described in example 35, suspended in dry acetonitrile (205 ml) under N2 was added with triphenylphosphine (42 g, 0.16 mole). The mixture was refluxed and after about 3 hours cooled and concentrated to give a solid, which was treated with ethyl ether, filtered and brought to dryness under vacuum. There were thus obtained 74 g of the title compound (yield: 84%).

1. temperatureThe mixture was refluxed and after about 3 hours
2. temperaturecooled
3. concentrationconcentrated
4. customto give a solid, which
5. filtrationfiltered