反应详情

In a stream of argon, 1.20 g (4.87 mmol) of 1-pyreneboronic acid, 1.50 g (3.03 mmol) of 2-(3,5-dibromophenyl)-4,6-di-p-tolyl-1,3,5-triazine and 57 mg (0.081 mmol) of dichlorobis-(triphenylphosphine)palladium were suspended in 135 mL of tetrahydrofuran, and the temperature of the obtained suspension was elevated to 70° C. 3.81 mL (15.2 mmol) of an aqueous 4N NaOH solution was gradually added dropwise to the suspension, and the obtained mixture was distilled under reflux for 2 hours. Then, 29 mg (0.041 mmol) of dichlorobis(triphenylphosphine)palladium was added, followed by distillation under reflux for 2 hours. Further, 0.20 g (0.81 mmol) of 1-pyreneboronic acid was added, followed by distillation under reflux for 2 hours. The resultant reaction mixture was left to stand to room temperature, and then distilled under a reduced pressure to remove all volatile materials. Methanol was added to the concentrate, and the thus-deposited solid was collected by filtration. The thus-obtained crude product was recrystallized from o-xylene. The recrystallization by o-xylene was repeated three times in total to give 1.14 g of the target 2-[3,5-di(1-pyrenyl)phenyl]-4,6-di-p-tolyl-1,3,5-triazine as grayish white solid (yield: 51%).

1. customwas elevated to 70° C
2. distillationthe obtained mixture was distilled
3. temperatureunder reflux for 2 hours
4. distillationfollowed by distillation
5. temperatureunder reflux for 2 hours
6. distillationfollowed by distillation
7. temperatureunder reflux for 2 hours
8. customThe resultant reaction mixture
9. waitwas left
10. customto stand to room temperature
11. distillationdistilled under a reduced pressure
12. customto remove all volatile materials
13. additionMethanol was added to the concentrate
14. filtrationthe thus-deposited solid was collected by filtration
15. customThe thus-obtained crude product
16. customwas recrystallized from o-xylene
17. customThe recrystallization by o-xylene