反应详情

To a solution of 1.82 g of 5,8,11,14,17-eicosapentaenic acid in 30 ml of dry chloroform was added 0.80 ml of oxalyl chloride under argon at room temperature. The mixture was reacted for 2 hours. From the reaction mixture was removed the chloroform and the removing oxalyl chloride by distillation under reduced pressure to give 5,8,11,14,17-eicosapentaenoyl chloride, which was then dissolved in 20 ml of dry chloroform.

1. customThe mixture was reacted for 2 hours
2. customFrom the reaction mixture was removed the chloroform
3. distillationthe removing oxalyl chloride by distillation under reduced pressure