反应详情

The product of Example 1E (73 mg, 0.323 mmol) and 4-chloro-6-phenylpyrimidin-2-amine (51 mg, 0.248 mmol) were treated under the conditions of Example 1F to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 7.84-7.93 (m, J=7.12, 2.37 Hz, 2H) 7.57-7.66 (m, 1H) 7.39-7.48 (m, 3H) 6.81-7.14 (m, 2H) 6.24 (s, 1H) 6.04 (s, 2H) 5.90 (s, 2H) 5.74 (d, J=5.76 Hz, 1H) 3.35-3.48 (m, 4H); MS (ESI+) m/z 323.0 (M+H)+.