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HRID2401100

反应详情

EQUATION

反应方程式

HRID 2401100 的结构方程式

REACTANTS

反应物

3
结构：C[C@H]1CCCCN1
HCID6427443

(2S)-2-Methylpiperidine

C6H13N

结构：Cc1ccc(S(=O)(=O)O[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1
HCID23560883

tert-Butyl (3R)-3-[(4-methylbenzene-1-sulfonyl)oxy]pyrrolidine-1-carboxylate

C16H23NO5S

结构：C[C@H]1CCCN1[C@H]1CCN(C(=O)OC(C)(C)C)C1
HCID59401846

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H]1CCCCN1[C@H]1CCN(C(=O)OC(C)(C)C)C1
HCID58468060

未命名化合物

收率 38%

PROCEDURE

实验过程

The title compound was prepared in a manner substantially the same as intermediate (xi), (2S,3′S)-2-methyl-[1,3′]bipyrrolidinyl-1′-carboxylic acid tert-butyl ester by condensing 3-(3R)-(toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester (5 g) with (S)-2-methyl-piperidine to obtain 1.5 g (38% yield) of the title compound as a beige oil.