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HRID2405477

反应详情

EQUATION

反应方程式

HRID 2405477 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：C=C(C)[C@@H]1CC[C@]2(C(=O)NCCCN(C)C(=O)OC(C)(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12
HCID67777052

未命名化合物

PRODUCTS

生成物

1
结构：C=C(C)[C@@H]1CC[C@]2(C(=O)NCCCNC)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12
HCID67773691

未命名化合物

PROCEDURE

实验过程

A vial containing methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-(3-(tert-butoxycarbonyl(methyl)amino)propylcarbamoyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate (122 mg, 0.164 mmol) was diluted with HCl (4M in dioxane) (3 mL, 12.00 mmol). The mixture was stirred at rt. After 1.5 h of stirring at rt, LC/MS indicated the reaction was complete. The mixture was concentrated under reduced pressure. The crude product was carried forward to the next step with no additional purification. LCMS: m/e 641.5 (M−H)−, 2.73 min (method 3).

WORKUP

后处理

  1. stirringAfter 1.5 h of stirring at rt
  2. concentrationThe mixture was concentrated under reduced pressure
  3. customThe crude product was carried forward to the next step with no additional purification
  4. customm/e 641.5 (M−H)−, 2.73 min (method 3)