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HRID242463

反应详情

EQUATION

反应方程式

HRID 242463 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)[C@H](N)CO
HCID2734079

(2S)-2-Amino-3,3-dimethyl-1-butanol

C6H15NO

结构：CNC(=O)[C@@H](NC(=O)n1nc(-c2ccc(F)c(F)c2)c2c1CCOC2)C(C)(C)C
HCID46834697

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)[C@@H](CO)NC(=O)n1nc(-c2ccc(F)c(F)c2)c2c1CCCC2
HCID46862571

未命名化合物

PROCEDURE

实验过程

Compound 51 was prepared according to the procedure described for the synthesis of compound 28 by replacing intermediate 16 with intermediate 18, and replacing tert-leucine methylamide with tert-leucinol. 1H NMR (CDCl3) δ 7.54-7.60 (m, 1H), 7.41-7.47 (m, 2H), 7.17-7.23 (m, 1H), 6.95 (dd, J=7.3, 3.4 Hz, 1H), 3.80-3.86 (m, 1H), 3.65-3.70 (m, 1H), 3.04 (m, 2H), 2.64 (m, 2H), 1.74-1.84 (m, 4H), 1.04 (s, 9H). LCMS (+ESI) m/z=378.3 [M+H]+.