反应详情

Preparation is effected analogously to Example 1, using 0.56 g (1.52 mmol) of N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,6-hexanediamine and the equimolar amount of N-cyano-O-phenyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]isourea as starting materials. Working up by chromatography analogously to Example 1 yields the purified title compound in the form of a viscous oil; MS (+FAB method): m/z (rel. int. [%])=669 ([M+H]+, 5), 121 (100); IR (KBr): 2163 cm-1 (C≡N). For analytical purposes a sample is converted into the tartaric acid salt in an ether/ethanol solvent mixture; m.p.: 79° C. (ether/ethanol).

1. customPreparation
2. customWorking up by chromatography analogously to Example 1 yields the
3. custompurified title compound in the form of a viscous oil