反应详情

Preparation is effected analogously to Example 63, using 0.20 g (0.6 mmol) of N-[2-[N-(4-fluorobenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,4-butanediamine and the equimolar amounts of 1,1'-carbonyldiimidazole and 2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethaneamine as starting materials. Working up by chromatography analogously to Example 63 yields the purified title compound in the form of a viscous oil. MS (+FAB method): m/z (rel. int. [%])=588 ([M+H]+, 2), 109 (100); IR (KBr): 1685 cm-1 (C=O); C27H38FN9OS2 (587.90).

1. customPreparation
2. customWorking up by chromatography analogously to Example 63 yields the
3. custompurified title compound in the form of a viscous oil