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HRID258623

反应详情

EQUATION

反应方程式

HRID 258623 的结构方程式

REACTANTS

反应物

3
结构：CCCC(C#CCBr)(CCC)OC(C)=O
HCID20327714

未命名化合物

结构：CCCC(C#CCN(CCCCCCC(=O)OCC)S(C)(=O)=O)(CCC)OC(C)=O
HCID20327720

未命名化合物

结构：CCCCC[C@H](C#CCBr)OC(C)=O
HCID22793816

未命名化合物

PRODUCTS

生成物

2
结构：CS(=O)(=O)N(CCCCCCC(=O)O)CCCC1(O)CCCCCCC1
HCID20327691

未命名化合物

结构：CCCCCC(/C=C/CN(CCCCCC(CC)C(=O)O)S(C)(=O)=O)OC(C)=O
HCID20327696

未命名化合物

PROCEDURE

实验过程

The synthesis of this compound is carried out as described in Example 3, except that, in Step A, the 1-bromo-4(R)-acetoxy-2-nonyne is replaced by an equimolar amount of 1-bromo-4-acetoxy-4-propyl-2-heptyne (Example W). The product of Step A is thus ethyl 7-[N-(4-acetoxy-4-propyl-2-heptynyl)methanesulfonamido]heptanoate. The subsequent steps yield 7-[N-(4-hydroxy-4-propyl-2-heptynyl)methanesulfonamido]heptanoic acid (B) and 7-[N-(4-hydroxy-4-propyhexyl)methanesulfonamido]heptanoic acid (C).

WORKUP

后处理

  1. customThe synthesis of this compound