反应详情

2-(2-Ethyl-4-oxo-4H-1-benzopyran-6-yl)propan-1-ol (4.1 g) was taken up in ethanol (100 ml), Raney Nickel (5.0 g) was added and the mixture hydrogenated at 45 psi for 2 hours. The catalyst was removed by filtration (Hyflo supercel) and replaced with a fresh batch (5.0 g) and hydrogenation at 45 psi continued for a further 3 hours. The catalyst was removed by filtration and the filtrate evaporated to yield 2-(2,3-dihydro-2-ethyl-4-oxo-4H-1-benzopyran-6-yl)propanol as a pale green oil (4.5 g), I.R. carbonyl absorption 1690 cms-1.

1. customThe catalyst was removed by filtration (Hyflo supercel)
2. waitcontinued for a further 3 hours
3. customThe catalyst was removed by filtration
4. customthe filtrate evaporated