反应详情

When (+) 10-ethyl-1,2,3,11a-tetrahydro-5 H-pyrrolo[2,1-c] [1,4] benzodiazepin-5,11(10H)-dione, melting point 138° -140°C., (prepared as described above by reacting N-ethylisatoic anhydride with L-proline) is substituted for (+)-1,2,3,11 a-tetrahydro-10-methyl-[5H-pyrrolo [2,1-c] [1,4] benzodiazepin-5,11 -(10H)-dione in the procedure of Example 1, the above compound is obtained. The hydrochloride salt melts at 233°-235°C., [α]D 25 + 415° (0.9% in methanol).

1. customthe above compound is obtained