反应详情

A mixture of the compound of Example I, C. (21.7 g., 0.1 mole) and p-n-butylaniline (14.9 g., 0.1 mole) in ethanol (200 ml.) was stirred and refluxed overnight. The reaction solution was concentrated to dryness by rotary evaporator and the residue was collected and dried at 100°C to yield 36.5 g. (99.7%) yellow crystals, m.p. 296°-303°C. A small sample (5.0 g.) was recrystallized from nitromethane (750 ml.) and dried to yield 1.9 g. yellow crystals, m.p. 287°-302°C. A repeated recrystallization gave m.p. 303°-306°C.

1. temperaturerefluxed overnight
2. concentrationThe reaction solution was concentrated to dryness by rotary evaporator
3. customthe residue was collected
4. customdried at 100°C
5. customto yield 36.5 g
6. customA small sample (5.0 g.) was recrystallized from nitromethane (750 ml.)
7. customdried
8. customto yield 1.9 g
9. customA repeated recrystallization
10. customgave m.p. 303°-306°C.