反应详情

The title compound was prepared in the manner described in Example 3 using 2-hydroxy-2-(3-trifluoromethylphenyl)ethanamine and (4-methylphenoxy)propan-2-one. The residual oil was chromatographed on Kieselgel 60. Elution with 5% methanol-chloroform gave the title compound m.p. 86-96 (heptane). τ(CDCl3) 8.9 (3H, d, J=6 Hz), 7.7 (3H, s), 6.7-7.6 (5H, m, 2H disappears with D2O) 6.0-6.5 (2H, m), 5.3 (1H, m), 3.25 (2H, d, J=9 Hz), 2.95 (2H, d, J=9 Hz), 2.3-2.65 (4H, m).

1. customThe title compound was prepared in the manner
2. customThe residual oil was chromatographed on Kieselgel 60
3. washElution with 5% methanol-chloroform