反应详情

Using deprotection method B, but without addition of anisole, 4-{(R)-2-[(3-chloro-1H-indole-6-carbonyl)amino]-2-phenylethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester (4.6 g crude, 8.97 mmol) afforded 5 g (100%) of the title compound as a crude residue, which was used without further purification.