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HRID333908

反应详情

EQUATION

反应方程式

HRID 333908 的结构方程式

REACTANTS

反应物

2
结构：O=c1cc(I)cc[nH]1
HCID20582535

4-Iodopyridin-2(1H)-one

C5H4INO

结构：C#Cc1ccc([C@H](C)N2CC[C@](CC(C)(C)O)(c3ccccc3)OC2=O)cc1
HCID86670541

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H](c1ccc(C#Cc2cc[nH]c(=O)c2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O
HCID49870703

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from (S)-3-((S)-1-(4-ethynylphenyl)ethyl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one and 4-iodopyridin-2(1H)-one following a procedure analogous to that described in Example 28 Step 3. LC-MS Method 1 tR=1.3 min, m/z=471 (M+1). 1H NMR (CD3OD) 7.44-7.28 (m, 8H), 6.97 (d, 2H), 6.64 (s, 1H), 6.44 (dd, 1H), 5.54 (q, 1H), 3.02 (dt, 1H), 2.49 (m, 2H), 2.21 (m, 1H), 2.15 (s, 2H), 1.53 (d, 3H), 1.26 (s, 3H), 0.96 (s, 3H).