反应详情

The title compound was prepared from the title A compound and (1aR-cis)-1a,7b-dihydro-2,2-dimethyl-2H-oxireno-[c][1]benzopyran-6-carbonitrile (the title A compound of Example 3) by the procedure described for the title compound of Example 1. The oily residue was purified by flash chromatography on silica gel (ethyl acetate:hexanes/1:6), to give a colorless powder (410 mg, 77%), mp 119°-124° C. [α]D =+54.40 (c=0.43, MeOH). Analysis calculated for C21 H24N2O3 : C, 71.57; H, 6.86; N, 7.95. Found: C, 71.53; H, 6.94; N, 7.73.

1. customThe oily residue was purified by flash chromatography on silica gel (ethyl acetate:hexanes/1:6)