反应详情

Subsequently, carboxyhexacyclo[6.6.1.13,6.110,13.02,7.09,14 ]heptadecen of 2.1 grams and 3,4-dihydro-2H-pyran of 1.71 grams were dissolved in tetrahydrofuran of 50 milli-litter, and p-toluen sulfonic acid of 0.03 gram was added to the solution. The reaction was continued at room temperature for 2 hours. The resultant material was diluted in ether of 100 milli-litter, and was washed in 3% solution of Na2CO3, saturated water of salt and water in this order, and the organic layer was dried with MgSO4. When ether and residual 3,4-dihydro-2H-pyran were removed in vacuum by using an evaporator, we obtained viscous-liquid of 12-tetrahydropyranyloxycarbonilhexacyclo[6.6.1.13,6.110,13.02,7.09,14 ]heptadecen of 2 grams.

1. additionwas added to the solution
2. washwas washed in 3% solution of Na2CO3, saturated water of salt and water in this order
3. dry with materialthe organic layer was dried with MgSO4
4. customWhen ether and residual 3,4-dihydro-2H-pyran were removed in vacuum
5. customan evaporator, we