huagongshe.com
HRID379893

反应详情

EQUATION

反应方程式

HRID 379893 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)O[C@@H](C)C(=O)Cl
HCID11094804

(S)-(-)-2-Acetoxypropionyl chloride

C5H7ClO3

结构：CCOC(=O)n1c(C(=O)c2cc(COC(C)=O)co2)c(N)c2ccc(Cl)cc21
HCID18367907

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)n1c(C(=O)c2cc(COC(C)=O)co2)c(NC(=O)[C@H](C)OC(C)=O)c2ccc(Cl)cc21
HCID54082255

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) employing 2-(4-acetoxymethyl-2-furoyl)-3-amino-6-chloro-1-(ethoxycarbonyl)indole (Example 373, step 2) and (S)-(−)-2-acetoxypropionyl chloride. 1H-NMR (CDCl3) δ: 10.03 (1H, br s), 8.26 (1H, d, J=1.81 Hz), 8.21 (1H, d, J=8.74 Hz), 7.62 (1H, s),7.30 (1H, dd, J=8.74 Hz, 1.81 Hz), 7.28 (1H, s), 5.38 (1H, q, J=6.92 Hz), 4.99 (2H, s), 4.12 (2H, q, J=7.09 Hz), 2.08 (3H, s), 2.04 (3H, s), 1.59 (3H, d, J=6.92 Hz), 1.26 (3H, t, J=7.09 Hz).