反应详情

An amidation reaction and post-treatment were carried out under the same conditions as in Example 19, using 1.61 g (6.99 mmol) of 4-amino-1-(4-methylbenzyl)-5-imidazole carboxamide which was prepared in the same manner as in Example 87 and nicotinic acid instead of cyclopentylacetic acid to obtain 1.43 g of 1-(4-methylbenzyl)-4-(3-pyridylcarbonylamino)-5-imidazolecarboxamide (yield 61%).

1. customAn amidation reaction