反应详情

In analogy to Example 22A, the title compound was prepared from ethyl 4-chloro-5,7-dihydro-6H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidine-6-carboxylate from Example 21A (100 mg, 0.35 mmol) and 3-chloro-4-[(3-fluorobenzyl)oxy]aniline from Example 4A (93 mg, 0.37 mmol) to give 157 mg (72% purity, 65% yield), which was used in the next step without purification.

1. customto give 157 mg (72% purity, 65% yield), which
2. customwas used in the next step without purification