HRID38912

反应详情

EQUATION

反应方程式

HRID 38912 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

Preparation according to Example 2 using [(2R)-7-(trifluoromethylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl-4-methylbenzenesulfonate (0.27 g, 0.68 mmol), ethanamine (1 ml, 70% in water) and ACN (2 ml). Yield: 0.170 g, 76%. The amine was converted to the hydrochloric acid salt and recrystallized from acetonitrile. M.p. 208° C. MS m/z (rel. intensity, 70 eV) 325 (M+, 1) 58 (bp), 56 (8), 79 (5), 59 (4). [α]=−40° (MeOH).

WORKUP

后处理

  1. customPreparation
  2. customrecrystallized from acetonitrile
  3. custom[α]=−40° (MeOH)