HRID38913
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
Preparation according to Example 2 using [(2R)-7-(trifluoromethylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl-4-methylbenzenesulfonate (0.39 g, 0.98 mmol), propan-1-amine (1 ml) and ACN (2 ml). Yield: 0.150 g, 45%. The amine was converted to the hydrochloric acid salt and recrystallized from acetonitrile. M.p. 175° C. MS m/z (rel. intensity, 70 eV) 339 (M+, 2) 310 (10), 270 (6), 72 (bp), 70 (6). [α]=+50° (MeOH).
WORKUP
后处理
- customPreparation
- customrecrystallized from acetonitrile
- custom[α]=+50° (MeOH)