反应详情

The title compound was prepared from di-tert-butyl {4-[1-(trans-4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-1H-pyrazol-4-yl]-2-(trimethylstannanyl)furo[2,3-c]pyridin-7-yl}imidodicarbonate and 7-bromo-5-(1H-pyrazol-3-yl)-1,2,3-benzothiadiazole by a procedure analogous to Example 373, Step B. 1H NMR (400 MHz, CD3OD): δ 1.50-1.61 (m, 2 H), 1.93-2.06 (m, 2 H), 2.13-2.21 (m, 2 H), 2.25-2.33 (m, 2 H), 3.75 (tdd, J=10.9, 10.9, 4.2, 4.0 Hz, 1 H), 4.27 (tdd, J=12.0, 12.0, 4.3, 4.1 Hz, 1 H), 6.97 (d, J=2.3 Hz, 1 H), 7.58 (s, 1 H), 7.78 (d, J=2.3 Hz, 1 H), 7.88 (s, 1 H), 7.93 (s, 1 H), 7.94 (s, 1 H), 8.92 (br. s, 1 H), 9.04 (d, J=1.3 Hz, 1 H).