反应详情

The title compound was prepared following procedure described for Intermediate 1, step 2, but starting from ethyl 5-cyano-6-methoxy-1H-indole-2-carboxylate obtained in step 1 (120 mg; 0.49 mmol) as a beige solid (135 mg, 99%). 1H NMR (DMSO-d5) δ 9.25 (s, 1H), 7.60 (s, 1H), 7.11 (s, 1H), 6.90 (s, 1H), 5.53 (bs, 2H), 4.31 (q, J=7 Hz, 2H), 3.80 (s, 3H), 1.32 (t, J=7 Hz, 3H).