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HRID401461

反应详情

EQUATION

反应方程式

HRID 401461 的结构方程式

REACTANTS

反应物

2
结构：O=Cc1cnc2ccc(Br)cn12
HCID21345676

6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde

C8H5BrN2O

2 次

结构：OB(O)c1cncc(C(F)(F)F)c1
HCID45158900

[5-(Trifluoromethyl)pyridin-3-yl]boronic acid

C6H5BF3NO2

PRODUCTS

生成物

1
结构：O=Cc1cnc2ccc(-c3cncc(C(F)(F)F)c3)cn12
HCID86670609

未命名化合物

收率 48%

PROCEDURE

实验过程

The title compound was prepared by following the procedure as described for Intermediate 1 using 6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde and 5-(trifluoromethyl)pyridin-3-ylboronic acid. Yield: 48%; 1H NMR (DMSO-d6; 300 MHz): δ 10.04 (s, 1H), 9.71 (s, 1H), 9.27 (s, 1H), 9.07 (s, 1H), 8.62 (s, 2H), 8.16-8.19 (dd, 1H, J=1.8&9.3 Hz), 8.03-8.04 (d, 1H, J=9.3 Hz); MS: m/z 292 (M+1)+.