反应详情

2.5 M of n-BuLi (3.1 mL/hexane, 7.67 mmol) was added to benzo[b]thiophene (1.05 g, 7.67 mmol/THF (20 mL)) and reacted at 0° C. for 1 hour under a dry and anaerobic operation condition to form a solution. SnBu3Cl (2.38 mL, 8.44 mmol) was then added to the solution and reacted at 0° C. for 30 minutes. After returning to room temperature, the solution was continuously reacted for 8 hours. After the reaction was completed, the solution was extracted by ether (30 mL) and deionized water (50 mL). An organic phase was collected. After removal of ether by a rotary concentrator, the organic phase was purified by reduced-pressure distillation to form a transparent pale yellow oily product (23, 1.76 g, 54%).

1. customreacted at 0° C. for 1 hour under
2. customa dry
3. customanaerobic operation condition to form a solution
4. customreacted at 0° C. for 30 minutes
5. customAfter returning to room temperature
6. customthe solution was continuously reacted for 8 hours
7. extractionthe solution was extracted by ether (30 mL) and deionized water (50 mL)
8. customAn organic phase was collected
9. customAfter removal of ether by a rotary concentrator
10. distillationthe organic phase was purified by reduced-pressure distillation
11. customto form a transparent pale yellow oily product (23, 1.76 g, 54%)