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HRID42088

反应详情

EQUATION

反应方程式

HRID 42088 的结构方程式

REACTANTS

反应物

2
结构：C=C1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)CC12
HCID67536381

未命名化合物

结构：C[C@]12CCCCC1[C@@H](C=O)C[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC13OCCOC12OCCO3
HCID86635567

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]12CCC(=O)CC1[C@@H](C=O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12
HCID86635566

未命名化合物

收率 85%

PROCEDURE

实验过程

6α-Formylandrostane-3,17-dione was prepared in 85% yield from 3,3:17,17-bis(ethylendioxy)-6α-formylandrostane (Prepn. 14) by the procedure described above for the preparation of 6-methyleneandrostane-3,17-dione (II-ac, Prepn. 13). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness to give 6α-formylandrostane-3,17-dione. 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 9.50 (1H, d), 2.56-0.82 (21H, m), 1.16 (3H, s), 0.88 (3H, s).

WORKUP

后处理

  1. washThe combined organic extracts were washed with H2O
  2. dry with materialdried over Na2SO4
  3. customevaporated to dryness
  4. customto give 6α-formylandrostane-3,17-dione