HRID44895

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C1CCCC1

HCID24820413

(7R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one

C14H19ClN4O

结构：C[Si](C)(C)CCOCn1ncc(B(O)O)c1-c1nccs1

HCID58405547

未命名化合物

PRODUCTS

生成物

结构：CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1C(C)C1CC1

HCID58405738

未命名化合物

PROCEDURE

实验过程

The title compound was prepared similarly to the methods described in Example 5, with Intermediate SS instead of Intermediate B and with 5-(thiazol-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-ylboronic acid (Boronic Acid 1) instead of pyridin-4-ylboronic acid. The resulting coupling product is then deprotected by the method described in Example 331 to give the title compound. LCMS: 410.1 m/z (M+H)+; ret. Time: 7.64 min. (Analytical Method C).

WORKUP

后处理

customThe title compound was prepared similarly to the methods