反应详情

The title compound was prepared in the same fashion as that for compound 222 from ethyl 3-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-1,2,4-oxadiazole-5-carboxylate and hydroxylamine hydrochloride. m/e+=370 (M+H+). 1H NMR (400 MHz, in DMSO-d6): δ 8.43-8.41 (1H, D, d, J=7.2 Hz, ArH), δ 8.31 (1H, D, s, ArH), δ 7.88-7.86 (2H, D, d, J=8.4 Hz, ArH), δ 7.65-7.62 (1H, D, d, J=9.2 Hz, ArH), δ 7.57-7.54 (1H, D, d, J=8.4 Hz, ArH), δ 7.35-7.31 (1H, D, t, J=8.0, ArH), δ 7.04-7.00 (1H, D, t, J=8.0, ArH), and δ 4.62 (2H, D, s, CH2).