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HRID459376

反应详情

EQUATION

反应方程式

HRID 459376 的结构方程式

REACTANTS

反应物

3
结构：Oc1ccc2c(c1)CCCC2
HCID14305

5,6,7,8-Tetrahydro-2-naphthalenol

C10H12O

结构：CO[C@@H](Cc1ccc(OCCCOc2ccccc2)cc1)C(=O)O
HCID58822897

未命名化合物

结构：COC(=O)C(Cc1cccc(OCCBr)c1)OC
HCID69423413

未命名化合物

PRODUCTS

生成物

1
结构：COC(Cc1cccc(OCCOc2ccc3c(c2)CCCC3)c1)C(=O)O
HCID18443260

2-Methoxy-3-{3-[2-(5,6,7,8-tetrahydro-naphthalen-2-yloxy)-ethoxy]-phenyl}-propionic acid

C22H26O5

PROCEDURE

实验过程

The title compound was prepared from 5,6,7,8-tetrahydro-naphthalen-2-ol and 3-[3-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid methyl ester (Example 351, Step 1) via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1). The enatiomers were separated by chiral HPLC. MS (ES) for C22H26O5 [M−H]−: 369.2.

WORKUP

后处理

  1. customThe enatiomers were separated by chiral HPLC