反应详情

Acenaphthenequinone, 9.1 g. (0.05m), and 10.3 g. (0.05m) of 4-amino-3-nitrobenzotrifluoride were hydrogenated at room temperature in 125 ml. of 2B ethanol with 2.5 g. of palladium-on-carbon (5 percent) at 50 psi. After 4 hours three equivalents of hydrogen were absorbed and the temperature rose to 40° C. The catalyst was filtered and the filtrate was diluted with 1.2 l. of ethanol. The reaction was completed by refluxing the ethanolic solution for about 1 hour. The precipitated product was collected to yield about 8 g. (50 percent yield) of 9-(trifluoromethyl)acenaphtho[1,2-b]quinoxaline, mp = 185°-186° C.

1. customwere hydrogenated at room temperature in 125 ml
2. customrose to 40° C
3. filtrationThe catalyst was filtered
4. additionthe filtrate was diluted with 1.2 l
5. temperatureby refluxing the ethanolic solution for about 1 hour
6. customThe precipitated product was collected
7. customto yield about 8 g