反应详情

The product from Example 29B and 2-[(1S,2S,55)-6,6-dimethylbicyclo[3.1.1]hept-2-yl]acetic acid (Eigenmann, G. W.; Arnold, R. T. JACS 1959, 81, 3440-2) were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 0.91 (d, J=9.76 Hz, 1H) 1.08 (s, 3H) 1.20 (s, 3H) 1.39-1.66 (m, 1H) 1.76-2.05 (m, 5H) 2.20-2.46 (m, 4H) 7.45-7.65 (m, 4H) 7.71 (dd, J=7.63, 1.83 Hz, 2H) 8.35 (d, J=5.19 Hz, 1H) 11.46 (s, 1H); MS (ESI) m/z 408 (M+H)+.