反应详情

The product of Example 1B and 2-(3-hydroxyadamantan-1-yl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 11.12 (s, 1H), 8.34 (dd, J=7.9, 1.3 Hz, 1H), 8.11 (d, J=8.1 Hz, 1H), 8.00 (ddd, J=8.3, 7.1, 1.3 Hz, 1H), 7.89 (ddd, J=8.0, 7.1, 1.0 Hz, 1H), 3.61 (p, J=6.7 Hz, 1H), 2.08-2.11 (m, 4H), 1.36-1.63 (m, 13H), 1.26 (d, J=6.7 Hz, 6H); MS (ESI) m/z 396 (M+H)+.