反应详情

3-(4-Methylhexyl)pyridine was prepared in a similar manner to that described above with regard to 3-hexylpyridine but using 3-methyl-1-pentylbromide [prepared by adding over 1 h, at -30° C. and under N2, 22.5 g of PBr3 (0.083 mol; 7.8 ml) to a mixture of 21.6 g (0.212 mol) of 3-methyl-1-pentanol, 3.95 g of anhydrous pyridine and 88.4 ml of anhydrous sulfuric ether; the mixture was allowed to react for 1 h at -30° C. and then for 1 night at room temperature; the reaction product was extracted and washed in the usual manner and purified on a Vigreux column to provide 20.8 g of pure product].

1. customprepared
2. additionby adding over 1 h, at -30° C. and under N2
3. customto react for 1 h at -30° C.
4. waitfor 1 night at room temperature
5. extractionthe reaction product was extracted
6. washwashed in the usual manner
7. custompurified on a Vigreux column