huagongshe.com
HRID493996

反应详情

EQUATION

反应方程式

HRID 493996 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1ccnc(Cl)c1
HCID5151595

2-Chloro-4-pyridylboronic acid

C5H5BClNO2

结构：CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCS(=O)(=O)CC4)cc3c2)CC1
HCID16739577

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCS(=O)(=O)CC2)n3-c2ccnc(Cl)c2)CC1
HCID16739647

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for the synthesis of example 5, the title compound was synthesized from (1,1-dioxo-thiomorpholin-4-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-methanone (Example 2) and 2-chloropyridine-4-boronic acid. The desired product was obtained in a yield of 8% as an off-white solid. MS (m/e): 531.5 (M+, 100%).

WORKUP

后处理

  1. customIn analogy to the procedure described for the synthesis of example 5