反应详情

The titled compound was prepared from 4-fluoro-2-amino-N-(2-pyridyl)aniline and (E)-3-Cyclohexylacryloyl chloride according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method A). MW: 321.40; mp: 109.1-110.1° C.; 1H-NMR (CDCl3) δ: 8.76-8.72 (1H, m), 7.97 (1H, ddd, J=7.7, 7.7, 2.0 Hz), 7.47-7.40 (3H, m), 7.34 (1H, dd, J=9.0, 4.8 Hz), 7.11 (1H, dd, J=15.7, 7.1 Hz), 6.97 (1H, ddd, J=9.0,9.0,2.5 Hz), 6.38 (1H, dd, J=15.7, 1.3 Hz), 2.27-2.10 (1H, m), 1.84-1.57 (5H, m), 1.37-1.09 (5H, m).